HEATmarker VVM and VVM+ indicators are affixed to a vaccine vial by the manufacturer to allow for full-life temperature monitoring. The inner square features a heat-sensitive material that becomes darker when exposed to heat. The colour change is faster at higher temperatures and slower at lower temperatures. At the end point, the inner square is the same colour as or darker than the outer circle. This allows the HEATmarker VVM to give health workers an overview of the cumulative heat exposure of the vaccine and a clear visual indication when it has reached its time-temperature end point, informing them whether the vaccine should be administered.
HEATmarker VVM 250 is optimal for use with very high stability vaccines, as defined by WHO/PQS/E006/IN05.3. It features a maximun time to end-point of 250 days at 37°C. Shelf life is 5 years.
HEATmarker VVM Fact Sheet R2, Doc #3189 | Download Fact Sheet Download Fact Sheet | |
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WHO/PQS/E006/IN05.4 Compliance | Learn More Learn More | |
WHO Testing Protocol | Learn More Learn More | |
WHO-UNICEF VVM Policy Statement | Learn More Learn More |